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レスベラトロールとサーチュイン遺伝子

2011/07/05  カテゴリー/生活の知恵

■ レスベラトロール
今テレビや新聞、雑誌などで大注目のレスベラトロール
体内の老化を遅らせる遺伝子(長寿遺伝子)であるサーチュイン遺伝子の活性化に関与している事がつきとめられました。

レスベラトロールは赤ブドウの皮などに多く含まれるポリフェノールの一種で、様々の病気の原因とされている「活性酸素」を抑える抗酸化作用が高いことが証明されています。

脳梗塞や心筋梗塞などのように、高コレステロールによってもたらされる症状を改善する働きが注目されています。

また、細胞の染色体の先端にある細胞の寿命を決定するテロメヤDNAを覆っているヒストンと言いうタンパク質がストレスなどによって壊れ、テロメヤDNAが露出し、短くなることが老化の原因とされていますが、レスベラトロールを投与すると、このヒストンを守るサーチュイン(Sir1)やサーツー(Sir2)といった長寿関連遺伝子が活性化されテロメヤDNAが外に露出することを防ぎます。

その結果、様々な病気や老化の予防につながり、長寿につながるということです。

ここをクリック ↓↓↓
       レスベラトロール ① ピオーネに多く含まれるレスベラトロール

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       レスベラトロール ②

■ サーチュイン遺伝子
サーチュイン遺伝子
はマサチューセッツ工科大学(MIT)の生物学部教授であるレオナルド・ギャランテ教授によって発見されました。

老化を遅らせ寿命を伸ばす因子として発見され、普段は活性化していない遺伝子ですが、空腹がある程度続く(カロリー制限する)とこの遺伝子のスイッチがONになり、活性化すると、生体の寿命が飛躍的に伸びるようになるというものです。

実験では、ショウジョウバエでは30%、線虫では50%以上寿命が長くなったとしています。

その他、サル等の実験でもカロリーコントロールによってサーチュイン遺伝子が活性化された結果、明らかに寿命が伸びたことが証明されています。

このサーチュイン遺伝子は人間では10番目の染色体にあることが分かっています。

NHKスペシャル 「あなたの寿命は延ばせる~発見!長寿遺伝子~」

貴方の「目」を「活性酸素」からしっかり守り、長寿遺伝子を活性化させる
レスベラトロール含有健康食品は・・・!

こちらをご覧ください ⇒ レスベラトロール含有食品







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